KPV
10 mg8% purityLot #KPV-2026-001
SKU of selected dimension: PEP-KPV-10MG
KPV (Lys-Pro-Val) is a naturally occurring tripeptide representing the C-terminal fragment of alpha-melanocyte stimulating hormone (α-MSH). Although composed of only three amino acids, it preserves the powerful anti-inflammatory actions of its parent hormone while lacking the pigment-producing (melanogenic) effects associated with α-MSH. Its primary mechanism involves preventing the nuclear translocation of NF-κB, one of the central regulators of inflammatory gene expression. Through this pathway, KPV helps decrease the production of key pro-inflammatory cytokines such as TNF-α, IL-6, and IL-1β. Research has highlighted its potential in inflammatory bowel disease, skin inflammation, and tissue repair models, where it supports the resolution of inflammation and promotes healing of damaged tissues.
€82.96incl. VAT
✅ In Stock (40)
Volume pricing
| Quantity | Unit price | Savings |
|---|---|---|
| 1 vial | 82.96 € | — |
| 3 vials (−7%) | 76.86 € | −7% |
| 5 vials (−12%) | 73.20 € | −12% |
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Research Profile
KPV — scientific profile
Content is for educational and research purposes. Research Use Only.
- KPV (Lys-Pro-Val) is a naturally occurring tripeptide representing the C-terminal fragment of alpha-melanocyte stimulating hormone (α-MSH). Although composed of only three amino acids, it preserves the powerful anti-inflammatory actions of its parent hormone while lacking the pigment-producing (melanogenic) effects associated with α-MSH. Its primary mechanism involves preventing the nuclear translocation of NF-κB, one of the central regulators of inflammatory gene expression. Through this pathway, KPV helps decrease the production of key pro-inflammatory cytokines such as TNF-α, IL-6, and IL-1β. Research has highlighted its potential in inflammatory bowel disease, skin inflammation, and tissue repair models, where it supports the resolution of inflammation and promotes healing of damaged tissues.
